16 mukhi rudraksha represents lord Shiva himself. 16 mukhi is a reservoir of healing properties and it is believed that it can help in chronic physical and mental ailments like cancer, TB, psoriasis, severe low back pain, sciatica, kidney stones, prostrate, schizophrenia, bipolar disorder and many more medically incurable diseases.  It also protects against panic attacks and invisible negative energies sent by tantric.